{"id":27744,"date":"2025-11-25T11:45:48","date_gmt":"2025-11-25T04:45:48","guid":{"rendered":"https:\/\/orientalheritageherbalists.com\/wp-staging\/?p=27744"},"modified":"2025-11-25T11:47:29","modified_gmt":"2025-11-25T04:47:29","slug":"artocarpus-lakoocha-roxb-a-powerhouse-for-skin-and-wellness","status":"publish","type":"post","link":"https:\/\/orientalheritageherbalists.com\/wp-staging\/artocarpus-lakoocha-roxb-a-powerhouse-for-skin-and-wellness\/","title":{"rendered":"Artocarpus lakoocha Roxb.: A Powerhouse for Skin Brightening and Wellness"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"27744\" class=\"elementor elementor-27744\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1f182869 e-flex e-con-boxed e-con e-parent\" data-id=\"1f182869\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7eba3841 elementor-widget elementor-widget-text-editor\" data-id=\"7eba3841\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\n<p><strong>Artocarpus lakoocha Roxb.<\/strong>, also known as <strong>Ma-haad<\/strong> or <strong>Monkey Jack<\/strong>, is a traditional Southeast Asian medicinal plant highly prized for its heartwood, which is rich in <strong>oxyresveratrol<\/strong>. This bioactive compound offers potent antioxidant, anti-pigmentation, and anti-inflammatory effects, making Ma-haad an increasingly valuable ingredient in <strong>cosmetics<\/strong>, <strong>supplements<\/strong>, and wellness products.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\">Key Active Compound: Oxyresveratrol<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The heartwood of A. lakoocha contains a high amount of <strong>oxyresveratrol<\/strong>, a polyphenolic stilbene known for very strong antioxidant activity and inhibition of the enzyme tyrosinase, which is involved in melanin synthesis.<\/li>\n\n\n\n<li>Pharmacognostic studies of this wood show consistent presence of oxyresveratrol across geographic sources, supporting quality and standardization. <\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\">Benefits in the Cosmetic Industry<\/h3>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Skin Brightening &amp; Pigmentation Control<\/strong>\n<ul class=\"wp-block-list\">\n<li>Research demonstrates that A. lakoocha heartwood extract strongly inhibits tyrosinase, the key enzyme in melanin production. <\/li>\n\n\n\n<li>Clinical (in vivo) trials in humans showed that using a topical solution of the extract reduced melanin in the skin over time.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Anti-Aging &amp; Antioxidant Protection<\/strong>\n<ul class=\"wp-block-list\">\n<li>In vitro studies show that both the extract and pure oxyresveratrol protect human fibroblasts from oxidative damage (e.g., caused by hydrogen peroxide or UV-A), and these protect cells as well or better than known antioxidants.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Photoprotective &amp; Anti-Inflammatory Effects<\/strong>\n<ul class=\"wp-block-list\">\n<li>More recent research demonstrated that oxyresveratrol from A. lakoocha suppresses inflammatory responses in human keratinocytes exposed to UVB radiation, by modulating signaling pathways like p38 MAPK and AP-1. <\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\">Benefits in Supplements &amp; Wellness<\/h3>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Powerful Antioxidant Activity<\/strong>\n<ul class=\"wp-block-list\">\n<li>Oxyresveratrol is a potent antioxidant that helps neutralize free radicals, supporting cellular health and longevity.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Neuroprotection<\/strong>\n<ul class=\"wp-block-list\">\n<li>In cell-based studies, oxyresveratrol and A. lakoocha extract protected neuroblastoma cells (SH-SY5Y) from oxidative stress caused by hydrogen peroxide, reducing reactive oxygen species (ROS) and lipid peroxidation. <\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Anti-Inflammatory &amp; Detox<\/strong>\n<ul class=\"wp-block-list\">\n<li>By reducing inflammation and oxidative stress, Ma-haad may support broader detoxifying effects and immune resilience. <\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\">Quality &amp; Extraction Insights<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>A recent development in \u201cgreen\u201d extraction has produced ready-to-use oxyresveratrol-enriched extracts using <strong>deep eutectic solvents (DES)<\/strong>. These extracts showed very high antioxidant and anti-tyrosinase activity, in one case, 252\u00d7 more anti-tyrosinase activity than kojic acid. <\/li>\n\n\n\n<li>Standardization of A. lakoocha heartwood is well studied: one paper reported that among different sources, the content of oxyresveratrol can be quantified reliably, which is important for manufacturing consistent, high-quality ingredients.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\">Why Artocarpus lakoocha is Trending in Modern Formulations<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Natural Alternative to Synthetic Brighteners<\/strong>: Oxyresveratrol offers effective skin-lightening without some of the risks associated with synthetic agents.<\/li>\n\n\n\n<li><strong>Multi-Functional Ingredient<\/strong>: Acts both as an antioxidant and a tyrosinase inhibitor, useful in anti-aging, skin-brightening, and wellness products.<\/li>\n\n\n\n<li><strong>Sustainable &amp; Standardizable<\/strong>: Good research on extraction, quality control, and standardization supports safe and reproducible use.<\/li>\n\n\n\n<li><strong>Consumer Appeal<\/strong>: Growing demand for \u201cheritage\u201d botanicals with traditional history and modern scientific validation.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\">Conclusion<\/h3>\n\n\n\n<p><strong>Artocarpus lakoocha Roxb.<\/strong> (Ma-haad) is a highly valuable botanical for both the cosmetic and supplement industries thanks to its rich content of <strong>oxyresveratrol<\/strong>,  a compound with strong antioxidant, anti-melanin, and anti-inflammatory properties. Backed by robust research, this herb can be a cornerstone for natural skin-brightening products, anti-aging formulas, and wellness supplements.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\">References<\/h3>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Panichakul T. et al. <em>Additive effect of a combination of Artocarpus lakoocha and Glycyrrhiza glabra extracts on tyrosinase inhibition in melanoma B16 cells.<\/em> Pharmaceuticals, 2020. <a href=\"https:\/\/www.mdpi.com\/1424-8247\/13\/10\/310?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">MDPI+2PubMed+2<\/a><\/li>\n\n\n\n<li>Tengamnuay P., Prugsakij W., Wongkajornsilp A. <em>In vitro evaluation of anti-aging activities of Artocarpus lakoocha heartwood extract.<\/em> Afr J Trad Complement Altern Med. <a href=\"https:\/\/journals.athmsi.org\/index.php\/ajtcam\/article\/view\/826?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">journals.athmsi.org<\/a><\/li>\n\n\n\n<li>International Journal of Pharmacy and Pharmaceutical Sciences. <em>Neuroprotective effect of Artocarpus lakoocha extract and oxyresveratrol against H2O2-induced toxicity in SH-SY5Y cells.<\/em> <a href=\"https:\/\/journals.innovareacademics.in\/index.php\/ijpps\/article\/view\/21827?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">IJP Pharmaceutics<\/a><\/li>\n\n\n\n<li>PubMed. <em>Suppression of the inflammatory response by oxyresveratrol from the root bark of Artocarpus lakoocha Roxb against UVB-induced keratinocytes.<\/em> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39469685\/?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">PubMed<\/a><\/li>\n\n\n\n<li>MDPI. <em>Development of a ready-to-use oxyresveratrol-enriched extract from Artocarpus lakoocha using deep eutectic solvents.<\/em> Cosmetics, 2024. <a href=\"https:\/\/www.mdpi.com\/2079-9284\/11\/2\/58?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noreferrer noopener\">MDPI<\/a><\/li>\n\n\n\n<li>Journal of Health Research. <em>Pharmacognostic study of Artocarpus lakoocha heartwood.<\/em><\/li>\n<\/ol>\n\n\n\n<p>Explore our website to learn more: <a href=\"https:\/\/orientalheritageherbalists.com\/wp-staging\/shop\/\">Click Here<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center\">Related Products<\/h2>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Artocarpus lakoocha Roxb., also known as Ma-haad or Monkey Jack, is a traditional Southeast Asian medicinal plant highly prized for its heartwood, which is rich in oxyresveratrol. This bioactive compound offers potent antioxidant, anti-pigmentation, and anti-inflammatory effects, making Ma-haad an increasingly valuable ingredient in cosmetics, supplements, and wellness products. Key Active Compound: Oxyresveratrol Benefits in [&hellip;]<\/p>\n","protected":false},"author":27,"featured_media":27745,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[44],"tags":[],"class_list":["post-27744","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cosmetics"],"_links":{"self":[{"href":"https:\/\/orientalheritageherbalists.com\/wp-staging\/wp-json\/wp\/v2\/posts\/27744","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/orientalheritageherbalists.com\/wp-staging\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/orientalheritageherbalists.com\/wp-staging\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/orientalheritageherbalists.com\/wp-staging\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/orientalheritageherbalists.com\/wp-staging\/wp-json\/wp\/v2\/comments?post=27744"}],"version-history":[{"count":5,"href":"https:\/\/orientalheritageherbalists.com\/wp-staging\/wp-json\/wp\/v2\/posts\/27744\/revisions"}],"predecessor-version":[{"id":27751,"href":"https:\/\/orientalheritageherbalists.com\/wp-staging\/wp-json\/wp\/v2\/posts\/27744\/revisions\/27751"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/orientalheritageherbalists.com\/wp-staging\/wp-json\/wp\/v2\/media\/27745"}],"wp:attachment":[{"href":"https:\/\/orientalheritageherbalists.com\/wp-staging\/wp-json\/wp\/v2\/media?parent=27744"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/orientalheritageherbalists.com\/wp-staging\/wp-json\/wp\/v2\/categories?post=27744"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/orientalheritageherbalists.com\/wp-staging\/wp-json\/wp\/v2\/tags?post=27744"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}